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Vol. 14. Issue 4.
Pages 413-418 (July - August 2010)
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Vol. 14. Issue 4.
Pages 413-418 (July - August 2010)
Brief communication
Open Access
Osteoarthritis in the neonate: risk factors and outcome
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Griselda Berberian1,
Corresponding author
griselberberian@yahoo.com.ar

Correspondence to: Pico 2265, 1429 Buenos Aires, Argentina. Tel.: +54-11-47031188.
, Verónica Firpo1, Adriana Soto1, Julio Lopez Mañan1, Cecilia Torroija1, Graciela Castro1, Pablo Polanuer2, Camilo Espinola2, José Luis Piñeiro3, María Teresa Rosanova1
1 Department of Infectious Diseases, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina
2 Orthopaedic Surgery, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina
3 Microbiology, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina
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Abstract
Objectives

The aim of this study was to identify the clinical, radiological, and bacteriological features, risk factors, and outcome of neonates with bone and joint infections.

Study design

Observational, retrospective, and analytical study of 77 patients less than 2 months of age, admitted to a tertiary neonatal intensive care unit (NICU) with the diagnosis of bone or joint infection, based on clinical, radiological, and microbiological criteria.

Results

Seventy-seven patients with 99 acute osteoarthritis foci in a 16 year period were included in the study. Risk factors for infection could be identified in 69% of the patients. The hip was the most frequent. Staphylococcus aureus was the main isolated microorganism. Twenty-nine infants (38%) had sequelae. Hip involvement, culture positive, and Staphylococcus aureus isolation were risk factors associated with sequelae.

Conclusion

Osteoarticular infection is unusual in the neonate; however it is associated with an elevated incidence of sequelae. This mandates for a high degree of suspicion to diagnose this potentially disabling entity.

Keywords:
osteoarthritis
neonate
Staphylococcus aureus
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The Brazilian Journal of Infectious Diseases
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