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Vol. 16. Issue 1.
Pages 82-85 (January - February 2012)
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Vol. 16. Issue 1.
Pages 82-85 (January - February 2012)
Open Access
Prevalence of antibodies to Borrelia burgdorferi sensu stricto in humans from a Cuban village
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Islay Rodrígueza,
Corresponding author
islay@ipk.sld.cu

Corresponding author at: Instituto de Medicina Tropical “Pedro Kourí”, Novia del Mediodía, km 6 1/2 – 00, La Lisa, Havana, Cuba.
, Carmen Fernándeza, Lizet Sáncheza, Bárbara Martínezb, Hans H. Siegristc, Reto Lienhardc
a Tropical Medicine Institute “Pedro Kourí”, Havana, Cuba
b Medical Assistant Centre of Sierra del Rosario, Artemisa, Cuba
c Laboratory of Microbiology, ADMed, La Chaux-de-Fonds, Switzerland
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Abstract

Lyme disease has not been officially reported in Cuba. However, clinical cases have been serologically reported. Seroprevalence survey of Borrelia burgdorferi sensu stricto antibodies in humans in the country has not been conducted.

Objective

To estimate the prevalence of borrelial antibodies in inhabitants of a village with historically high level of tick infestation.

Methods

Serum specimens from 247 persons randomly selected from the population of the village were examined by IgG Western blot using B31 strain for estimating the prevalence of antibodies profile.

Results

A seroprevalence value interval (95% CI) of 0.6%–7.2% was estimated for the studied population. The prevalent borrelial protein bands on immunoblots were 41, 72, 90/93, 34, 47, 60, 58, 56, 65/66 and 31 kDa in a decreasing order of significance.

Conclusion

These results support the previous serological findings, suggesting the presence of this borreliosis in Cuba.

Keywords:
Borrelia burgdorferi
Prevalence
Lyme disease
Antibodies
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