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Pathogenesis of HTLV-1 infection and progression biomarkers: An overview
2021, Brazilian Journal of Infectious DiseasesCitation Excerpt :RT is responsible for the transcription of single-stranded RNA into a double-stranded DNA molecule, which integrates into the genome of the host cell, becoming proviral DNA [19,21,23]. HTLV-1/2 share molecular and biological characteristics [11,21,24], and the integration of viral nucleic acids into the cellular genome establishes viral persistence and maintains and transmits the virus, which determines the various outcomes of infection [21]. HTLV-1/2 infect lymphocytes that are found in various body fluids, including blood, semen, vaginal secretions, and breast milk.
Human lymphotropic viruses associated with lymphoid malignancy: Epstein-Barr and HTLV-1
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Copyright © 1986 Published by Elsevier Inc.